A ruby in the rubbish: beneficial mutations, deleterious mutations and the evolution of sex.
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چکیده
منابع مشابه
A ruby in the rubbish: beneficial mutations, deleterious mutations and the evolution of sex.
This study presents a mathematical model in which a single beneficial mutation arises in a very large population that is subject to frequent deleterious mutations. The results suggest that, if the population is sexual, then the deleterious mutations will have little effect on the ultimate fate of the beneficial mutation. However, if most offspring are produced asexually, then the probability th...
متن کاملDeleterious mutations and the evolution of sex.
It has been suggested that sexual reproduction is maintained because it reduces the load imposed by recurrent deleterious mutations. If rates of deleterious mutation per diploid genome per generation (U) exceed 1, and mutations interact synergistically, then sexuals can overcome their inherent twofold disadvantage. We have tested this hypothesis by estimating genomic point mutation rates for pr...
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This study presents a mathematical model that allows for some offspring to be dispersed at random, while others stay close to their mothers. A single genetic locus is assumed to control fertility, and this locus is subject to the occurrence of deleterious mutations. It is shown that, at equilibrium, the frequency of deleterious mutations in the population is inversely related to the rate of dis...
متن کاملSex and deleterious mutations.
The evolutionary advantage of sexual reproduction has been considered as one of the most pressing questions in evolutionary biology. While a pluralistic view of the evolution of sex and recombination has been suggested by some, here we take a simpler view and try to quantify the conditions under which sex can evolve given a set of minimal assumptions. Since real populations are finite and also ...
متن کاملThe Role of Deleterious and Beneficial Mutations in the Evolution of Ploidy Levels
All sexual organisms experience a haploid and a diploid phase during their life cycle, yet the extent of each phase is remarkably variable. We explore the evolution of a locus that alters the timing of meiosis, hence altering the proportion of the life cycle spent in either the haploid or diploid phase. Evolution ofthe life cycle will occur in response to viability selection acting at fitness l...
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ژورنال
عنوان ژورنال: Genetics
سال: 1994
ISSN: 1943-2631
DOI: 10.1093/genetics/137.2.597